Related Experiment Video
Updated: Jul 12, 2026

Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
Parameters of quantitative trait loci
1Department of Orthopedics Surgery, Campbell Clinic, University of Tennessee Health Science Center, Memphis, TN, USA.
Abstract:
Most traits of medical relevance follow quantitative inheritance patterns. The genetic dissection of quantitative traits poses special challenges for geneticists mainly because of low penetrance and gene-gene and gene-environment interactions. Emerging genome resources and technologies are enabling systematic investigation of the genetic architecture of quantitative traits in more efficient ways. This article summarizes the current state of medical quantitative trait locus (QTL) mapping-describing the methods, limitations, and achievements in the detection and characterization of QTLs.
Related Concept Videos
Polygenic Traits
Polygenic Traits
Multiple Allele Traits
Multiple Allele Traits
Dihybrid Crosses
X-linked Traits
