Related Experiment Videos
Prevention of atopic disease in at risk newborns
1Department of Pediatrics, University of Roma La Sapienza Medical School, Italy.
Insights
Preventing childhood atopic diseases involves understanding genetic factors and early screening. Identifying high-risk infants allows for timely dietary and environmental interventions to reduce atopic responses.
Area of Science:
- Pediatrics
- Immunology
- Genetics
Background:
- Atopic diseases affect at least 15% of children.
- Genetic predisposition is a significant factor in atopy development.
Purpose of the Study:
- To highlight the importance of early screening for atopic diseases.
- To emphasize the role of environmental and dietary interventions in prevention.
Main Methods:
- Screening family history for atopic disease.
- Measuring serum immunoglobulin E (IgE) in cord blood.
Main Results:
- Early identification of at-risk infants through screening.
- Potential for intervention through dietary and environmental modifications.
Conclusions:
- Early detection and intervention are key to preventing childhood atopy.
- Modifiable environmental and dietary factors play a crucial role in the atopic response.
Abstract:
At least 15% of children have at least one atopic disease and genetic factors play an important role in the development. Screening of family history and high serum cord IgE permits introduction of dietary and environmental measures to prevent atopy. Environmental, prenatal, perinatal factors, exposure to household allergens, infections, cigarette smoking, dietary factors, including those during pregnancy, duration of breast feeding, dietary measures during lactation, all have effects in modifying the atopic response.