Related Experiment Video

Updated: Jul 12, 2026

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
11:56

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells

Published on: April 11, 2014

Ascorbic Acid as a factor controlling the development of cyanide-insensitive respiration.

O Arrigoni, R Arrigoni-Liso, G Calabrese

    Science (New York, N.Y.)
    |October 15, 1976
    PubMed
    Summary

    Lycorine blocks a respiration process in potato tubers by inhibiting ascorbic acid. Adding ascorbic acid reverses this effect, suggesting its role in protein synthesis for respiration.

    More Related Videos

    Intra-cardiac Side-Firing Light Catheter for Monitoring Cellular Metabolism using Transmural Absorbance Spectroscopy of Perfused Mammalian Hearts08:51

    Intra-cardiac Side-Firing Light Catheter for Monitoring Cellular Metabolism using Transmural Absorbance Spectroscopy of Perfused Mammalian Hearts

    Published on: May 12, 2019

    High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells08:33

    High-resolution Respirometry to Assess Mitochondrial Function in Permeabilized and Intact Cells

    Published on: February 8, 2017

    Related Concept Videos

    Chemical Factors Affecting Respiration Centers01:31

    Chemical Factors Affecting Respiration Centers

    Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
    CO2 has a potent influence on respiration and is strictly regulated. Under...
    Factors Affecting Respiration01:24

    Factors Affecting Respiration

    Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
    Other Factors Affecting Respiration Centers01:17

    Other Factors Affecting Respiration Centers

    Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
    However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical level,...
    The Electron Transport Chain01:30

    The Electron Transport Chain

    The electron transport chain or oxidative phosphorylation is an exothermic process in which free energy released during electron transfer reactions is coupled to ATP synthesis. This process is a significant source of energy in aerobic cells, and therefore inhibitors of the electron transport chain can be detrimental to the cell's metabolic processes.
    Inhibitors of the electron transport chain
    Rotenone, a widely used pesticide, prevents electron transfer from Fe-S cluster to ubiquinone or Q in...
    Physiological Control of Respiration01:23

    Physiological Control of Respiration

    Introduction
    Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
    Regulation of Ventilation
    The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
    Respiratory Regulation of Acid-Base Balance01:18

    Respiratory Regulation of Acid-Base Balance

    Respiratory compensation is a vital physiological process that stabilizes blood plasma pH by regulating the partial pressure of carbon dioxide (PCO2), a key determinant of pH levels. Most carbon dioxide in the blood dissolves and converts into carbonic acid (H2CO3). It dissociates into hydrogen ions (H+) and bicarbonate ions (HCO3⁻). There is also an inverse relationship between PCO2​​ and pH.
    When carbon dioxide levels increase in the blood, more H+ and HCO3⁻ are produced, leading to a...