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Necrotizing eccrine squamous syringometaplasia presenting as acral erythema
F Rongioletti1, A Ballestrero, F Bogliolo
1Department of Dermatology, University of Genoa, Italy.
Journal of Cutaneous Pathology
|December 1, 1991
Abstract:
Acral erythema (AE) and eccrine squamous syringometaplasia (ESS) are distinctive clinico-pathological entities described in patients receiving chemotherapy for malignancies, mainly myelogenous leukemia. In no case of chemotherapy-induced AE have histopathologic changes of ESS been described. We report a patient with acute myelogenous leukemia who had typical AE due to cytarabine with histopathologic ESS. The latter findings in a case of AE may be a useful diagnostic clue for distinguishing chemotherapy-induced AE from palmo-plantar erythema of graft-vs-host reaction.