Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunologic aspects of chronic sinusitis.

V J Lund1, G K Scadding

  • 1Institute of Laryngology and Otology, London, England.

The Journal of Otolaryngology
|December 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

EUFOREA summit in Brussels 2025: inspiring the future of allergy and respiratory care.

Frontiers in allergy·2026
Same author

Development and psychometric validation of the Chronic Rhinosinusitis Control Test.

Rhinology·2025
Same author

Indication for biologics in a real-world cohort of dupilumab treated chronic rhinosinusitis with nasal polyps patients according to international recommendations: evidence from the European CRS Outcome Registry (CHRINOSOR).

Rhinology·2025
Same author

ULANC - EUFOREA workshop 2024: bringing the concept of global airways to the frontline of medical care.

Frontiers in allergy·2025
Same author

Raising the bar in respiratory care by EUFOREA: report of the European Union Parliament Symposium, April 2024.

Frontiers in allergy·2025
Same author

Pocket guide: biologics in upper and lower airways in adults.

Rhinology·2025
Same journal

Primary large cell neuroendocrine carcinoma of the submandibular gland: unique presentation and surprising treatment response.

The Journal of otolaryngology·2008
Same journal

Hearing recovery after meningitis.

The Journal of otolaryngology·2008
Same journal

Endoscopic transnasal sphenopalatine arterial ligation for intractable posterior epistaxis in a young child.

The Journal of otolaryngology·2008
Same journal

[Non-functional parathyroid cyst].

The Journal of otolaryngology·2008
Same journal

Cacosmia secondary to an olfactory groove meningioma.

The Journal of otolaryngology·2008
Same journal

Hemangioma of the vocal cords: review of two cases.

The Journal of otolaryngology·2008
See all related articles

Immunological defense is crucial for chronic sinusitis, but its prevalence is unknown. This study found that deficiencies in minor immunoglobulin G subclasses may be overlooked when only the major class is measured, impacting treatment.

Area of Science:

  • Immunology
  • Otolaryngology
  • Infectious Diseases

Background:

  • Chronic sinusitis involves complex immunological defense mechanisms.
  • The exact incidence of immune system problems in sinusitis remains unclear.
  • Major immunoglobulin G (IgG) class measurement may not reveal all immune deficiencies.

Purpose of the Study:

  • To investigate the role of immunological defense in chronic sinusitis.
  • To determine the incidence of serum immunoglobulin abnormalities in patients with chronic rhino-sinusitis.
  • To highlight the importance of assessing IgG subclasses in sinusitis.

Main Methods:

  • A prospective study involving 47 patients diagnosed with chronic rhino-sinusitis.
  • Examination of serum immunoglobulins, including major classes and subclasses.

Related Experiment Videos

  • Analysis of potential correlations between immunoglobulin deficiencies and sinusitis.

    • Main Results:

    • Abnormalities in serum immunoglobulins were observed in patients with chronic rhino-sinusitis.
    • Deficiencies in minor IgG subclasses were identified as potentially significant.
    • These deficiencies might be missed if only the major IgG class is assessed.

    Conclusions:

    • Immunoglobulin deficiencies, particularly in minor IgG subclasses, are relevant to chronic sinusitis.
    • Specific assessment of IgG subclasses is recommended for clinically suspicious cases.
    • Understanding these immune issues has clinical and therapeutic implications for sinusitis management.