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GRASE (Gradient- and spin-echo) imaging: a novel fast MRI technique.
1Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Magnetic Resonance in Medicine
|August 1, 1991
Summary
Gradient- and spin-echo (GRASE) imaging offers a fast multi-section MR technique. It minimizes artifacts from field inhomogeneity and chemical shift, enabling clear T2-weighted images.
Area of Science:
- Medical Imaging
- Magnetic Resonance Imaging (MRI)
Background:
- Magnetic Resonance Imaging (MRI) is crucial for non-invasive diagnostics.
- Traditional MRI techniques can be limited by speed and image artifacts.
- Static field inhomogeneity and chemical shift are common sources of image degradation.
Purpose of the Study:
- To introduce and describe a fast multi-section MR imaging technique.
- To address and overcome image artifacts inherent in conventional MRI.
- To leverage gradient- and spin-echo principles for enhanced imaging.
Main Methods:
- Development of a Gradient- and Spin-Echo (GRASE) imaging sequence.
- Implementation of a novel k-space trajectory for signal modulation.
- Utilizing Hahn spin echoes to determine image contrast.
Main Results:
- Achieved significantly faster multi-section MR imaging acquisition.
- Successfully overcame image artifacts caused by static field inhomogeneity.
- Effectively mitigated artifacts related to chemical shift.
- Image contrast is reliably determined by T2 weighting in Hahn spin echoes.
Conclusions:
- GRASE imaging provides a viable solution for rapid, artifact-reduced MRI.
- The technique enhances image quality by addressing key artifact sources.
- This method offers a valuable advancement for clinical MRI applications.