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Updated: Aug 14, 2026

Phenotyping Mouse Pulmonary Function In Vivo with the Lung Diffusing Capacity
Published on: January 6, 2015
[Disorders of the pulmonary function in patients with destructive tuberculosis]
Abstract:
A complex clinicophysiological examination of 100 patients with destructive pulmonary tuberculosis has shown that the most common manifestations of pulmonary dysfunctions in this category of patients are functional changes in lung tissue as hyperinflation and restriction of the lungs and rise or decline of their elasticity. Disorders of bronchial patency and pulmonary gas exchange are second in their detection rate. The most important changes in pulmonary tissue function are hyperinflation and rise of elasticity; disorders of bronchial patency and pulmonary gas exchange are most commonly manifested by impaired minor bronchi and declined lung capacity. Lung restriction and decreased lung tissue elasticity are rather rare. Arterial hypoxemia is mainly found at rest.
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