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Updated: Jul 12, 2026
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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Initial evaluation of prostate cancer with real-time elastography based on step-section pathologic analysis after
Masahiro Sumura1, Kazushi Shigeno, Taiju Hyuga
1Department of Urology, Shimane University School of Medicine, Shimane, Japan. sumura@med.shimane-u.ac.jp
Summary
Real-time elastography shows promise for detecting prostate cancer. This non-invasive method, combined with ultrasound, achieved high detection rates, especially for larger tumors.
Area of Science:
- Urology
- Medical Imaging
- Oncology
Background:
- Prostate cancer diagnosis often relies on invasive procedures.
- Developing non-invasive detection methods is crucial for early diagnosis and treatment.
Purpose of the Study:
- To evaluate the efficacy of real-time elastography (RTE) in detecting prostate cancer.
- To assess RTE as a non-invasive diagnostic tool based on tissue strain values.
Main Methods:
- Seventeen patients undergoing radical prostatectomy were assessed using RTE.
- RTE findings were compared with digital rectal examination (DRE), transrectal ultrasonography (TRUS), color Doppler ultrasonography (CDUS), magnetic resonance imaging (MRI), and pathological results.
Main Results:
- Real-time elastography detected 20 out of 27 pathologically confirmed prostate tumors.
- Detection rates were superior to other modalities, with 75.0% on the anterior and 73.7% on the posterior prostate.
- Higher detection rates were observed for tumors with higher Gleason scores and larger volumes.
Conclusions:
- Real-time elastography, particularly when used with gray-scale TRUS, is a promising non-invasive modality for prostate cancer detection.
- This technique offers a valuable addition to existing diagnostic tools for prostate cancer.
