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Updated: Jul 12, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
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Two human ARFGAPs associated with COP-I-coated vesicles

Gabriella Frigerio1, Neil Grimsey, Martin Dale

  • 1Department of Clinical Biochemistry, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge CB2 2XY, United Kingdom.

Traffic (Copenhagen, Denmark)
|September 1, 2007
PubMed
Summary

ADP-ribosylation factor-GTPase-activating proteins (ARFGAPs) ARFGAP2 and ARFGAP3 are identified as key regulators of COP-I-dependent vesicular transport. Their function in the Golgi complex is essential for cell viability, highlighting their critical role in intracellular trafficking.

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