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Published on: January 8, 2016
Biosensing and drug delivery by polypyrrole
S Geetha1, Chepuri R K Rao, M Vijayan
1Centre for Conducting Polymers, Electrochemical Materials Science Division, Central Electrochemical Research Institute, Karaikudi 630006, India.
Analytica Chimica Acta
|September 1, 2007
Summary
Conducting polypyrrole, a biocompatible polymer, shows promise for biosensors and drug delivery systems. Electrochemical methods enable efficient drug release and biomolecule detection.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Electrochemistry
Background:
- Conducting polypyrrole is a biocompatible polymer matrix suitable for incorporating drugs and enzymes.
- Electropolymerized freestanding polypyrrole films are recognized for sophisticated electronic measuring devices.
- Polypyrrole's properties make it valuable in sensor technology and drug delivery applications.
Purpose of the Study:
- To review the applications of conducting polypyrrole in biosensing.
- To discuss the use of conducting polypyrrole in drug delivery systems.
- To highlight polypyrrole's efficiency as a biosensor in the presence of enzymes.
Main Methods:
- Electrochemical polymerization to obtain freestanding polypyrrole films.
- Doping techniques for incorporating drugs and enzymes into the polymer matrix.
- Review of existing literature on polypyrrole applications in biosensing and drug delivery.
Main Results:
- Conducting polypyrrole serves as an effective matrix for drug and enzyme incorporation.
- Electrochemical methods allow for 100% drug release upon potential reversal.
- Polypyrrole demonstrates high efficiency as a biosensor, particularly with enzyme integration.
Conclusions:
- Conducting polypyrrole is a versatile material for advanced biosensor development.
- Its application in drug delivery systems offers efficient and controlled release mechanisms.
- Further research into polypyrrole-based systems holds significant potential for biomedical applications.
