Clear cell hidradenoma of the ankle

Clear cell hidradenoma is a relatively common, benign eccrine neoplasm with rare presentations in the foot and ankle. Variable clinical and histopathologic characteristics of the tumor warrant careful consideration over primary and recurrent malignancy, particularly eccrine carcinoma. The first known case of primary benign clear cell hidradenoma of the ankle is presented with imaging studies, surgical management, and clinicopathologic correlation, distinguishing the neoplasm from its malignant counterparts.