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Related Concept Videos

Liver Histology01:27

Liver Histology

The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...

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Related Experiment Video

Updated: Jul 12, 2026

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
08:41

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

Published on: March 24, 2023

[Liver and focal liver contrast: radiologic-pathologic correlation].

V Laurent1, S Corby, L Antunes

  • 1Service de Radiologie Adultes, Hôpital de Brabois, Allée du Morvan, 54500 Vandoeuvre les Nancy. v_croiselaurent@yahoo.fr

Journal De Radiologie
|September 1, 2007
PubMed
Summary

Understanding liver lesion histology aids radiologists in interpreting imaging features. Advances in imaging techniques offer new insights for improved diagnosis.

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DUCT: Double Resin Casting followed by Micro-Computed Tomography for 3D Liver Analysis
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Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

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Last Updated: Jul 12, 2026

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
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Published on: March 24, 2023

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DUCT: Double Resin Casting followed by Micro-Computed Tomography for 3D Liver Analysis

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Published on: December 2, 2013

Area of Science:

  • Radiology
  • Histopathology
  • Medical Imaging

Context:

  • Liver lesions require accurate diagnosis.
  • Radiologists interpret imaging features to understand lesion characteristics.
  • Histological features influence lesion imaging.

Purpose:

  • To correlate histological features of liver lesions with their imaging characteristics.
  • To highlight the role of extracellular architecture in lesion appearance.
  • To emphasize the diagnostic value of advanced imaging techniques.

Summary:

  • Histological knowledge of liver lesions is crucial for radiologists.
  • Imaging features are influenced by extracellular matrix variations.
  • Advanced imaging offers enhanced spatial, temporal, and contrast resolution for better lesion analysis.

Impact:

  • Improved diagnostic accuracy for liver lesions.
  • Enhanced understanding of the relationship between histology and imaging.
  • Potential for earlier and more precise detection of liver abnormalities.