Related Experiment Video
Updated: Jul 12, 2026

10:40
Uniportal Full Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
Bony fusion through an empty cervical disc interspace implant
J Schröder1, C Schul, M Hasselblatt
1Department of Neurosurgery, University Clinics Münster, Münster, Germany. j.schroder@web.de
Zentralblatt Fur Neurochirurgie
|September 1, 2007
Summary
Solid bone fusion can occur within an empty cervical intervertebral cage, even without bone grafting. This finding is crucial for evaluating fusion in titanium implants and considering bone graft alternatives.
Area of Science:
- Spinal surgery
- Orthopedic implants
- Bone fusion biology
Background:
- Cervical intervertebral cages often feature holes for bone grafting to promote fusion.
- The necessity of filling these holes and assessing fusion, particularly with titanium implants, remains debated.
- Current evaluation of bony fusion is challenging and often limited to problematic cases.
Observation:
- A case of recurrent issues years after anterior cervical discectomy with a titanium cage, without bone grafting, was analyzed.
- The patient underwent revision surgery, and the cage contents were examined histologically.
- Radiographic assessment indicated successful fusion prior to revision.
Findings:
- Histological examination revealed solid bone formation within the hollow intervertebral cage.
- This demonstrates that complete bony bridging can occur through an empty implant.
Implications:
- The capacity for spontaneous bone formation within empty implants challenges current fusion assessment protocols.
- This finding has significant implications for the ongoing discussion regarding bone substitutes and bone graft alternatives in cervical fusion.
- Future research should consider the potential for fusion in empty cages when evaluating treatment outcomes.
Related Concept Videos
Structural Joints: Cartilaginous Joints
As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Degenerative Disc Disease I: Introduction
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
Articulations of the Vertebral Column
In addition to being held together by the intervertebral discs, adjacent vertebrae also articulate with each other at synovial joints formed between the superior and inferior articular processes called zygapophysial joints (facet joints). These are plane joints that provide for only limited motions between the vertebrae. The orientation of the articular processes at these joints varies in different regions of the vertebral column and serves to determine the types of motions available in each...