Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Increased Intracranial Pressure l: Introduction01:14

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
Increased Intracranial Pressure ll: Pathophysiology01:29

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure01:16

Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Surface-Topography Challenge: A Multi-Laboratory Benchmark Study to Advance the Characterization of Topography.

Tribology letters·2025
Same author

Radiation Therapy Combined With 5-Aminolevulinic Acid: Effect on Primary Human Meningioma Cells.

Clinical oncology (Royal College of Radiologists (Great Britain))·2025
Same author

iMPI: portable human-sized magnetic particle imaging scanner for real-time endovascular interventions.

Scientific reports·2023
Same author

[Borderline personality disorder: state of knowledge and attitudes among french-speaking mental health professionnals].

L'Encephale·2022
Same author

Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry·2021
Same author

Normal Load and Counter Body Size Influence the Initiation of Microstructural Discontinuities in Copper during Sliding.

ACS applied materials & interfaces·2021
Same journal

De novo contralateral vertebral artery dissection after treatment: incidence and clinical characteristics.

Acta neurochirurgica·2026
Same journal

Comparative analysis of the efficacy and safety of dural sealants in preventing complications after craniotomy: a systematic review and Bayesian network meta-analysis.

Acta neurochirurgica·2026
Same journal

OpenOR - a virtual reality framework for medical education.

Acta neurochirurgica·2026
Same journal

Vascular-based compartmental resection of anterior clinoidal meningiomas: an inter-perforator microdebulking strategy.

Acta neurochirurgica·2026
Same journal

How I do it: microvascular decompression for classical trigeminal neuralgia by arterial compression.

Acta neurochirurgica·2026
Same journal

From antimicrobial-impregnated to standard catheters for external ventricular drainage: a single-center before-and-after cohort study.

Acta neurochirurgica·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

Induction of Cerebral Arterial Gas Embolism in Rat
06:26

Induction of Cerebral Arterial Gas Embolism in Rat

Published on: October 18, 2024

Hyperbaric oxygen in neurosurgery.

B R Fischer1, E J Speckmann, C Greiner

  • 1Department of Neurosurgery, University Hospital of Münster (UKM), Albert-Schweitzer-Strasse 33, 48129, Münster, Germany.

Acta Neurochirurgica
|March 12, 2009
PubMed
Summary
This summary is machine-generated.

Hyperbaric oxygen therapy (HBOT) is crucial for increasing oxygen in brain tissues with impaired blood flow, minimizing damage. Modern evidence supports HBOT for treating neural tissue injury.

More Related Videos

Oxygen-Glucose Deprivation and Reoxygenation as an In Vitro Ischemia-Reperfusion Injury Model for Studying Blood-Brain Barrier Dysfunction
08:56

Oxygen-Glucose Deprivation and Reoxygenation as an In Vitro Ischemia-Reperfusion Injury Model for Studying Blood-Brain Barrier Dysfunction

Published on: May 7, 2015

Related Experiment Videos

Last Updated: Jun 24, 2026

Induction of Cerebral Arterial Gas Embolism in Rat
06:26

Induction of Cerebral Arterial Gas Embolism in Rat

Published on: October 18, 2024

Oxygen-Glucose Deprivation and Reoxygenation as an In Vitro Ischemia-Reperfusion Injury Model for Studying Blood-Brain Barrier Dysfunction
08:56

Oxygen-Glucose Deprivation and Reoxygenation as an In Vitro Ischemia-Reperfusion Injury Model for Studying Blood-Brain Barrier Dysfunction

Published on: May 7, 2015

Area of Science:

  • Neurology
  • Oxygen Therapy
  • Neurosurgery

Background:

  • Therapeutic use of pure oxygen under hyperbaric conditions established for 50 years.
  • Oxygen discovered 250 years prior to its therapeutic applications.
  • Neurosurgical patients frequently experience brain tissue damage from various causes.

Observation:

  • Impaired blood flow, obstructive vessel disease, and traumatic brain injury are common causes of neurosurgical patient brain damage.
  • Pure oxygen application is the sole method to elevate tissue O(2) concentration in compromised blood supply areas.
  • Hyperbaric oxygenation (HBO) specifically addresses insufficient oxygen supply to central neural tissue.

Findings:

  • Pure oxygen application minimizes secondary brain tissue impairment in neurosurgical patients.
  • Modern biological methods and study designs confirm HBO's role in treating neural tissue damage.
  • Evidence supports hyperbaric oxygenation as an effective treatment modality.

Implications:

  • Hyperbaric oxygen therapy offers a vital treatment option for neurosurgical patients with brain tissue damage.
  • Further research utilizing modern methods can enhance evidence-based applications of HBO.
  • HBO represents a significant advancement in managing central neural tissue oxygenation deficits.