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Digital-signal-processor-based dynamic imaging system for optical tomography.

Joseph M Lasker1, James M Masciotti, Matthew Schoenecker

  • 1Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace MC8904, New York, NY 10027, USA.

The Review of Scientific Instruments
|September 4, 2007
PubMed
Summary
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This study presents a novel dynamic optical tomography system utilizing digital signal processing for real-time imaging. The advanced digital system offers high speed, low noise, and excellent stability for accurate tissue phantom analysis.

Area of Science:

  • Biomedical Optics
  • Medical Imaging Technology
  • Digital Signal Processing

Background:

  • Current analog optical tomography systems have limitations in data acquisition and filtering.
  • There is a need for advanced instrumentation capable of real-time dynamic imaging.
  • Digital techniques offer potential for improved performance and accuracy in optical tomography.

Purpose of the Study:

  • To introduce a novel dynamic optical tomography system based on digital data acquisition and filtering.
  • To demonstrate the system's capability for real-time imaging at high frame rates.
  • To evaluate the system's performance in terms of noise, precision, stability, and dynamic range.

Main Methods:

  • Development of a continuous wave optical tomography instrument centered around a digital signal processor (DSP).

Related Experiment Videos

  • Implementation of synchronously timed processes managed by a complex programmable logic device and the DSP.
  • Design of a graphical user interface using LABVIEW for automated calibration, data acquisition, and postprocessing.
  • Utilized digital data acquisition and filtering techniques for signal processing.

    • Main Results:

    • The system achieves real-time data acquisition rates up to 150 Hz.
    • Demonstrated very low system noise (approx. 1 pW rms noise equivalent power).
    • Exhibited excellent signal precision (<0.04%-0.2%) and long-term stability (<1% over 40 min).
    • Large dynamic range (approx. 190 dB) suitable for various measurement geometries and tissue types.

    Conclusions:

    • The developed dynamic optical tomography system offers superior performance compared to analog systems.
    • The digital approach enables accurate capture of dynamic behavior and precise spatial tracking in tissue phantoms.
    • This technology holds promise for advanced biomedical imaging applications.