Three-dimensional echocardiographic evaluation of myocardial perfusion

One of the most intriguing developments in ultrasound imaging of the heart was the use of contrast media to assess myocardial perfusion, which sparked tremendous interest and over the years generated a significant body of research. Although most published work has been based on the use of contrast for 2D perfusion imaging, there are a few recent studies aimed at exploring the idea of 3D assessment of myocardial perfusion, which has the potential to overcome many of the limitations of the 2D methodology. We provide a brief overview of the 2D work that provided the scientific basis for the emerging 3D methodology and discuss the unique features and promises as well as the challenges posed by this novel approach.