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Updated: Jul 12, 2026

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea
Published on: February 21, 2016
Centrioles want to move out and make cilia
Chad G Pearson1, Brady P Culver, Mark Winey
1MCD Biology, University of Colorado, Boulder, CO 80309, USA. chad.pearson@colorado.edu
Abstract:
Cilia formation in mammalian cells requires basal bodies that are either derived from centrioles that transition from their cytoplasmic role in centrosome organization or that form en masse in multiciliated cells. Several recent studies have begun to uncover the links between centriole duplication and their transformation to basal bodies.
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