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Updated: Jul 12, 2026
12:12
Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
Published on: February 8, 2016
Review article: yeast as probiotics -- Saccharomyces boulardii
D Czerucka1, T Piche, P Rampal
1INSERM U 526, Faculté de Médecine, Université Nice-Sophia Antipolis, Nice Cedex 2, France. czerucka@unice.fr
Alimentary Pharmacology & Therapeutics
|September 5, 2007
Summary
Saccharomyces boulardii, a beneficial yeast probiotic, effectively treats and prevents various diarrheal conditions, including antibiotic-associated diarrhea. Research also suggests its potential in managing inflammatory bowel diseases and recurrent Clostridium difficile infections.
Area of Science:
- Microbiology
- Gastroenterology
- Immunology
Background:
- Probiotics are live microorganisms conferring health benefits.
- While most probiotics are bacteria, Saccharomyces boulardii is a notable yeast strain with proven efficacy.
- Saccharomyces boulardii has demonstrated effectiveness in double-blind clinical studies.
Purpose of the Study:
- To differentiate yeast from bacterial properties.
- To review Saccharomyces boulardii's characteristics and probiotic potential.
- To explore its therapeutic applications.
Main Methods:
- Literature search of PubMed and Medline databases.
- Keywords included 'probiotics', 'yeast', 'Saccharomyces boulardii', 'diarrhea', and 'inflammatory bowel disease'.
- Combinations of keywords were used to identify relevant studies.
Main Results:
- Saccharomyces boulardii has been studied for treating and preventing various diarrheas.
- Promising research indicates potential for inflammatory bowel disease maintenance therapy.
- The mechanisms underlying Saccharomyces boulardii's action are being elucidated.
Conclusions:
- Saccharomyces boulardii is a well-researched yeast probiotic.
- Its clinical activity is significant for antibiotic-associated diarrhea and Clostridium difficile infections.
- Emerging data supports its role as an 'immunobiotic' with novel therapeutic uses.
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