Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Parenteral Anesthetics: Overview

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

General Anesthesia: Overview

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...

Cystic Fibrosis: Management

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Preoperative Challenges for Pediatric Ambulatory Surgery.

International anesthesiology clinics·2024

Same author

Caffeine Use in the Anesthetic Management of a Patient With Congenital Central Hypoventilation.

Cureus·2022

Same author

Effects of Premedication With Midazolam on Recovery and Discharge Times After Tonsillectomy and Adenoidectomy.

Cureus·2021

Same author

PEDIATRIC ENDOTRACHEAL INTUBATION.

Middle East journal of anaesthesiology·2015

Same author

Perioperative chlorhexidine allergy: Is it serious?

Journal of anaesthesiology, clinical pharmacology·2015

Same author

Anaesthesia and orphan disease: anaesthesia for Gomez-Lopez-Hernandez syndrome.

European journal of anaesthesiology·2014

Search research articles

Related Experiment Video

Updated: Jul 12, 2026

Transforaminal Full-Endoscopic Lumbar Foraminotomy Under Local Anesthesia for L5/S1 Adjacent Segment Foraminal Stenosis

Transforaminal Full-Endoscopic Lumbar Foraminotomy Under Local Anesthesia for L5/S1 Adjacent Segment Foraminal Stenosis

Published on: October 17, 2025

Anesthesia for fucosidosis.

Claude Abdallah¹, Raafat Hannallah, Willis McGill

¹Division of Anesthesia and Pain Medicine, Children's National Medical Center, Washington, DC 20010, USA. cabdalla@cnmc.org

Paediatric Anaesthesia

|September 5, 2007

Summary

Fucosidosis is a rare genetic disorder affecting enzyme activity. This case highlights successful dental rehabilitation under anesthesia for a child with fucosidosis type 2.

Area of Science:

Biochemistry
Genetics
Pediatric Medicine

Background:

Fucosidosis is an autosomal recessive lysosomal storage disease caused by alpha-fucosidase deficiency.
It is an extremely rare condition with significant clinical manifestations.

Observation:

A 6-year-old child diagnosed with fucosidosis type 2 underwent dental rehabilitation.
The procedure was performed under general anesthesia.

Findings:

The anesthesia management for this patient with fucosidosis was uneventful.
This case provides insight into the clinical features of fucosidosis.

Implications:

Highlights the importance of careful anesthetic management in rare genetic disorders.

Related Experiment Videos

Last Updated: Jul 12, 2026

Transforaminal Full-Endoscopic Lumbar Foraminotomy Under Local Anesthesia for L5/S1 Adjacent Segment Foraminal Stenosis

Transforaminal Full-Endoscopic Lumbar Foraminotomy Under Local Anesthesia for L5/S1 Adjacent Segment Foraminal Stenosis

Published on: October 17, 2025

Contributes to the understanding of fucosidosis clinical presentation and management.

Underscores the need for multidisciplinary care in pediatric patients with lysosomal storage diseases.