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Updated: Jul 12, 2026

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
Published on: September 1, 2018
[Comparative evaluation of healthy preschool children blink]
Marcelo Mendes Lavezzo1, Silvana Artioli Schellini, Carlos Roberto Padovani
1Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil.
Insights
Spontaneous eye blink rate in children aged 4-6 increases with age. Blink duration and speed show no gender differences, though eyelid closure is slower than opening.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Neuroscience
Background:
- Spontaneous blinking is a fundamental physiological process.
- Understanding normal blink patterns in children is crucial for diagnosing potential visual or neurological issues.
Purpose of the Study:
- To evaluate spontaneous blink activity in the primary eye position in normal preschool children.
- To analyze blink rate, duration, and eyelid movement times in relation to age and gender.
Main Methods:
- Prospective evaluation of 200 normal children aged 4-6 years.
- Digital videography in a standard setting, capturing frontal and lateral views.
- Measurement of blink times and eyelid movement rhythm using frame scale and specialized software.
Main Results:
- Complete eye blinks were more frequent than incomplete blinks.
- Blink rate significantly increased with age.
- Eyelid opening and closing times, and complete blink duration were similar between genders.
Conclusions:
- The rate of complete eye blinks increases with age in preschool children.
- Eyelid closure time is slower than opening time.
- No significant gender-based differences were observed in blink characteristics.
Purpose:
To evaluate spontaneous blink activity in the primary eye position in normal preschool children.
Methods:
Two hundred normal children aged 4 to 6 years were prospectively evaluated. They were digitally videotaped in a standard setting, taking the images on frontal and lateral plans, during the vigil state, in the primary eye position. The object of observation was located at the same level of the pupil. A Sony Lithium camera was used. The images were recorded on 8 mm tapes and transferred to a personal computer (MacIntosh G4) and processed with the iMovie software. Opening, closure and total blink times were measured using frame scale. The eyelid movement rhythm per minute was also evaluated, during three minutes. The data were submitted to statistical analysis.
Results:
The complete eye blink was more frequently observed than the incomplete eye blink. The blink rate increased with age. The incomplete blink rate was the same for all the evaluated ages. The eyelid opening and closing times and the complete blink time were similar for both sexes, during all evaluation moments. There were no differences between genders regarding eye blink. The closing eyelid time was slower than the opening eyelid time.
Conclusions:
The complete blink rate increases with age. The closing and the opening eyelid times and the complete blink were similar for both sexes in all evaluated ages and the opening time is faster than the closing time.
