[Leiomyomatosis peritonealis disseminata]

Area of Science:

• Gynecologic Pathology
• Surgical Pathology
• Abdominal Imaging

Background:

• Leiomyomatosis peritonealis disseminata (LPD) is a rare condition involving benign smooth muscle cell proliferation.
• It typically affects premenopausal women, suggesting hormonal influences in its pathogenesis.
• Macroscopically, LPD can be mistaken for peritoneal carcinomatosis.

Observation:

• A case of LPD is presented in a 40-year-old woman.
• The patient underwent surgical intervention.
• The condition is often asymptomatic, with diagnosis confirmed histologically.

Findings:

• Microscopic examination is crucial for diagnosing LPD.
• Less than 100 cases of LPD have been documented globally.
• The subperitoneal nodules are composed of benign smooth muscle cells.

Implications:

• Accurate diagnosis of LPD is essential to differentiate it from malignant conditions.
• Understanding the hormonal role may guide future management strategies.
• Increased awareness can improve recognition of this uncommon entity.