Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Visual System01:26

Visual System

Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
The Retina01:32

The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A disinhibitory basal forebrain-to-cortex projection supports sustained attention.

Cell·2026
Same author

Protocol for mapping neural circuit connectivity with START: Single transcriptome assisted rabies tracing.

STAR protocols·2026
Same author

Genome-Wide Translatome Analysis Following Low-Dose Ketamine to Reveal Novel Targets for Antidepressant Treatment.

Synapse (New York, N.Y.)·2025
Same author

Asymmetric cortical projections to striatal direct and indirect pathways distinctly control actions.

eLife·2025
Same author

Microendoscopic calcium imaging in motor cortices of macaques during rest and movement.

iScience·2025
Same author

Complementary Organization of Mouse Driver and Modulator Cortico-thalamo-cortical Circuits.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025

Related Experiment Video

Updated: Jul 12, 2026

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
10:05

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

Published on: May 7, 2017

Specialized circuits from primary visual cortex to V2 and area MT.

Jonathan J Nassi1, Edward M Callaway

  • 1Systems Neurobiology Laboratories, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Neuron
|September 6, 2007
PubMed
Summary

Neurons in the primary visual cortex

Area of Science:

  • Neuroscience
  • Visual Processing
  • Cellular Biology

Background:

  • The primary visual cortex integrates magnocellular (M) and parvocellular (P) visual streams.
  • Layer 4B of the visual cortex projects to dorsal areas but contains diverse cell types, complicating input-output understanding.

Purpose of the Study:

  • To differentiate cell types and projection targets of layer 4B neurons.
  • To elucidate the cellular basis for specialized visual processing pathways.

Main Methods:

  • Utilized a modified rabies virus for retrograde tracing and green fluorescent protein expression.
  • Analyzed cell morphology, dendritic length, and laminar position of projecting neurons.

Main Results:

  • Layer 4B neurons projecting to MT are predominantly spiny stellate, while those projecting to V2 are mainly pyramidal.

More Related Videos

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

Related Experiment Videos

Last Updated: Jul 12, 2026

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity
10:05

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

Published on: May 7, 2017

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings
07:08

Investigating Object Representations in the Macaque Dorsal Visual Stream Using Single-unit Recordings

Published on: August 1, 2018

Cross-Modal Multivariate Pattern Analysis
13:51

Cross-Modal Multivariate Pattern Analysis

Published on: November 9, 2011

  • MT-projecting neurons exhibit larger cell bodies, greater dendritic length, and deeper laminar positioning.
  • MT-projecting pyramidal neurons are situated beneath cytochrome oxidase blobs, suggesting M-pathway input specificity.
  • Conclusions:

    • Layer 4B neurons projecting to MT are specialized for rapid M-pathway information transmission.
    • V2-projecting neurons likely handle slower processing involving combined M and P pathway signals.