Related Experiment Video
Updated: Jul 12, 2026

Low-Dose Gamma Radiation Sterilization for Decellularized Tracheal Grafts
Published on: April 14, 2023
Irradiated homograft cartilage in laryngotracheal reconstruction--a preliminary experience
Stacey L Smith1, Kevin D Pereira
1Department of Otolaryngology-H & N Surgery, The University of Texas-Houston Health Science Center, UTPB 1200, 6410 Fannin, Houston, TX 77030, United States.
Objective:
To determine the suitability of irradiated homograft cartilage in pediatric laryngotracheal reconstruction (LTR).
Methods:
Retrospective case series at a tertiary care children's hospital. Pediatric patients with subglottic stenosis who had LTRs performed using irradiated homograft costal cartilage. Data was collected on postoperative complications, findings at subsequent endoscopic examinations and final outcome.
Results:
Minor degrees of graft resorption were observed that did not affect eventual decannulation.
Conclusion:
Irradiated homograft costal cartilage can serve as a successful alternative to the traditional autologous costal cartilage in lower grades of laryngotracheal stenosis.

