Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...

Electrocardiogram

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Amyloid Positron Emission Tomography Imaging at the Onset of Amyloid-Related Abnormalities With Edema in an Alzheimer's Disease Patient.

Cureus·2026

Same author

MRI-Based Medial Temporal Atrophy May Reflect Amyloid PET Positivity in Cognitively Normal Individuals: A Preliminary Study.

Cureus·2025

Same author

Underestimated Centiloid Values in Amyloid PET: A Technical Report on Clinically Relevant Quantification Errors.

Cureus·2025

Same author

Safety of switching from lecanemab to donanemab in 20 consecutive patients with Alzheimer's disease.

Journal of Alzheimer's disease : JAD·2025

Same author

The Cingulate Island Sign is Useful for a Differential Diagnosis of Early-Onset Alzheimer's Disease and Dementia with Lewy Bodies: A 99mTc-ECD SPECT Study.

Juntendo Iji zasshi = Juntendo medical journal·2024

Same author

A Pilot Study on Cerebral Blood Flow and Mini-Mental State Examination to Predict Amyloid Deposition in Preclinical Alzheimer's Disease.

Psychiatry and clinical psychopharmacology·2024

Search research articles

Related Experiment Video

Updated: Jul 12, 2026

Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation

Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation

Published on: June 17, 2013

Prolonged and fluctuating giant T-wave inversion after electroconvulsive therapy.

Masanobu Ito¹, Kotaro Hatta, Koichi Miyakawa

¹Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan. masa110@med.juntendo.ac.jp

The Journal of ECT

|September 7, 2007

Summary

Electroconvulsive therapy (ECT) can cause T-wave inversion, a cardiac anomaly, in patients with severe depression. This effect may be exacerbated by additional stressors like gallbladder stone pain.

More Related Videos

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation (tACS)

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation (tACS)

Published on: January 22, 2016

Related Experiment Videos

Last Updated: Jul 12, 2026

Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation

Simultaneous EEG Monitoring During Transcranial Direct Current Stimulation

Published on: June 17, 2013

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation (tACS)

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation (tACS)

Published on: January 22, 2016

Area of Science:

Cardiology
Neurology
Psychiatry

Background:

Electroconvulsive therapy (ECT) is a treatment for severe depression.
Cardiac monitoring is crucial during ECT due to potential cardiovascular effects.

Observation:

A 76-year-old woman developed T-wave inversion after her third ECT session.
The T-wave inversion recurred weeks later, coinciding with gallbladder stone pain.

Findings:

Giant T-wave inversion appeared after the third ECT treatment, persisting for 4 months.
Exaggerated sympathetic stimulation from ECT may induce a cardiomyopathy-like state.
Gallbladder stone pain potentially exacerbated the cardiac condition.

Implications:

ECT-induced T-wave inversion may be linked to sympathetic overstimulation.
Comorbid conditions and pain can influence ECT's cardiac side effects.
Further research is needed to understand and manage ECT-related cardiac events.