Related Experiment Video
Updated: Jul 11, 2026

Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
Lactate in veterinary critical care: pathophysiology and management
1Department of Anaesthesia, Faculty of Veterinary Medicine, Companion Animal Clinic, University of Montreal, Saint-Hyacinthe, Quebec, Canada.
Abstract:
The measurement of blood lactate in people has proven to be a useful tool in the diagnosis, monitoring, and prognosis of a wide range of clinical syndromes. Its use in small animals is increasing, and several studies have been completed that demonstrate its potential role in critical care. This article summarizes the current state of knowledge regarding the physiology and pathophysiology of lactate production and lactic acidosis; current indications and the utility of measurement in a critical care setting are described; novel applications in the evaluation of cavitary effusions are highlighted; and a guide to the therapy of lactic acidosis is presented.
Related Concept Videos
Acute Pancreatitis II: Clinical Manifestations and Management
Diabetic Ketoacidosis ll: Pathophysiology
Diabetic Ketoacidosis l: Introduction
Acute Pancreatitis II: Pathophysiology
Diagnosing Acidosis and Alkalosis
First, the pH level is assessed to determine whether the blood pH is normal (7.35–7.45), low (acidosis), or high (alkalosis).
Next, the PCO2 and HCO3− values are examined to...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
