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Super-resolution Fluorescence Microscopy01:37

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Conducting Multiple Imaging Modes with One Fluorescence Microscope
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McArthur revisited: fluorescence microscopes for field diagnostics.

David Jones1, Julius Nyalwidhe, Laurence Tetley

  • 1Department of Experimental Orthopaedics and Biomechanics, Philipps University, Baldingerst, 35033 Marburg, Germany. jones@post.med.uni-marburg.de

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Summary

The McArthur microscope, invented by John Norris McArthur, is a classic portable field microscope. Its compact design and specialized lenses have been crucial for malaria diagnosis for decades.

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Area of Science:

  • Microscopy
  • Medical Diagnostics
  • Instrument Design

Background:

  • The McArthur microscope, developed by John Norris McArthur in the 1930s, addressed the need for a portable field instrument.
  • Its design facilitates field trips and has been instrumental in tropical medicine.
  • The microscope's development involved innovative folding of the optical path within a compact form factor.

Discussion:

  • The McArthur microscope is renowned for its compact dimensions (102x63x51mm) and robust performance.
  • It incorporates phase-contrast and specialized oil immersion objective lenses for enhanced visualization.
  • Its enduring utility is highlighted by its use in malaria diagnosis over several decades.

Key Insights:

  • The McArthur microscope exemplifies successful eponymous scientific instrument design.
  • Its portability and specialized optical features made it ideal for field use, particularly in tropical medicine.
  • The instrument's design has been adapted, including a later plastic version for educational purposes.

Outlook:

  • Further adaptations of the McArthur microscope design could enhance its application in remote or resource-limited settings.
  • Continued use in malaria diagnosis underscores the lasting impact of its innovative design.
  • The legacy of the McArthur microscope inspires the development of future portable diagnostic tools.