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Related Concept Videos

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
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Pneumonia I: Introduction01:30

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Related Experiment Video

Updated: Jul 11, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Infections associated with long-term prosthetic devices.

Marta Fernandez Sampedro1, Robin Patel

  • 1Division of Infectious Diseases, Department of Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

Infectious Disease Clinics of North America
|September 11, 2007
PubMed
Summary

Prosthetic device infections are rare but serious complications. Advances in understanding microbial-device-host interactions are key to improving diagnosis and treatment of these challenging infections.

Related Experiment Videos

Last Updated: Jul 11, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Area of Science:

  • Biomedical Engineering
  • Infectious Diseases
  • Medical Microbiology

Background:

  • Long-term prosthetic devices significantly enhance patient quality of life and survival.
  • Prosthetic device-related infections, though infrequent, cause substantial morbidity and mortality.
  • Current management necessitates prolonged antimicrobial therapy and surgical intervention, highlighting treatment challenges.

Purpose of the Study:

  • To review recent diagnostic and therapeutic advancements for infections linked to indwelling medical devices.
  • To focus on infections associated with specific high-risk prosthetic devices.
  • To emphasize the importance of understanding microorganism, device, and host interactions.

Main Methods:

  • Literature review of recent studies on prosthetic device infections.
  • Synthesis of current knowledge on diagnosis and treatment strategies.
  • Highlighting key findings related to common prosthetic devices.

Main Results:

  • Infections associated with prosthetic joints, cerebrospinal fluid shunts, and prosthetic heart valves are discussed.
  • Recent diagnostic tools and treatment modalities are presented.
  • The review underscores the complexity of managing these infections.

Conclusions:

  • Improved understanding of the microorganism-device-host interplay is crucial for effective management.
  • Advances in diagnosis and treatment offer better prospects for combating prosthetic device infections.
  • Continued research is needed to further refine therapeutic approaches and minimize patient morbidity.