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Intramembranous particle distribution and filipin binding in dysplastic canine retina
H E Whiteley1, R A Bergstrom, J R Scott
1Department of Veterinary Pathobiology, University of Illinois, Urbana 61801.
Current Eye Research
|November 1, 1991
Abstract:
We examined dysplastic canine retina for changes in intramembranous particle (IMP) density and filipin binding to sterols. Differences in IMP density were identified in incipiently dysplastic fetal retina and also in the degree of filipin binding near the onset of the dysplastic process. The data suggest that there are temporal differences in IMPs and filipin-sterol complexes that may be related to the formation of retinal folds and disorganized dysplastic retina proliferation.