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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
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Published on: June 29, 2016

Individual Antigenic Specificity of Isolated Antibodies

H G Kunkel, M Mannik, R C Williams

    Science (New York, N.Y.)
    |June 14, 1963
    PubMed

    Antisera produced against certain isolated human antibodies showed clear antigenic differences between these antibodies. Individual antigenic specificity was demonstrated for two anti-A antibodies, one anti-dextran, and one anti-levan antibody. Failure to produce specific antisera in other instances appeared to be correlated with a greater heterogeneity of the antibody population used as antigen.

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