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Published on: April 2, 2018
Isolable oxysulfuranes in organic chemistry.
Science (New York, N.Y.)
|January 16, 1976
Summary
New synthetic methods allow the study of hypervalent sulfur compounds called oxysulfuranes. Cyclization enhances reactivity, enabling the design of stable, isolable sulfurane reagents for various applications.
Area of Science:
- Chemistry
- Hypervalent Sulfur Chemistry
Background:
- Synthetic methods for oxysulfuranes have advanced, yielding a variety of isolable hypervalent sulfur compounds.
- Structure-reactivity relationships in these compounds are emerging from ongoing research.
Purpose of the Study:
- To explore the synthesis and reactivity of oxysulfuranes.
- To leverage cyclization-induced reactivity changes for designing novel sulfurane reagents.
Main Methods:
- Development of synthetic routes for oxysulfuranes.
- Investigation of structure-reactivity correlations.
- Synthesis and characterization of cyclic oxysulfuranes.
Main Results:
- A diverse range of isolable oxysulfurane compounds are now accessible.
- Clear structure-reactivity correlations are becoming apparent.
- Cyclic oxysulfuranes exhibit distinct reactivity profiles.
Conclusions:
- The dicoordinate nature of oxygen in oxysulfuranes facilitates cyclization.
- Cyclization offers a strategy for designing stable, isolable, and potentially useful sulfurane reagents.
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