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Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Jul 11, 2026

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

Published on: May 31, 2024

Regional cerebral blood flow using quantitative MR angiography.

M Zhao¹, S Amin-Hanjani, S Ruland

¹Department of Neurosurgery, University of Illinois at Chicago, IL 60612-5970, USA. mzhao@uic.edu

AJNR. American Journal of Neuroradiology

|September 12, 2007

Summary

Quantitative MR angiography (qMRA) was used to measure cerebral blood flow in 12 distinct brain regions. This study established normative flow values for regional cerebral blood flow in healthy adults.

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Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling

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Published on: July 28, 2018

Area of Science:

Neuroimaging
Cerebrovascular Physiology
Medical Physics

Background:

Cerebral blood flow (CBF) is a critical indicator of brain health.
Accurate measurement of regional CBF is essential for diagnosing and monitoring neurological conditions.

Purpose of the Study:

To derive regional cerebral blood flow (CBF) using vessel flows quantified by magnetic resonance angiography (qMRA).
To establish normative CBF values for distinct brain regions in a healthy adult population.

Main Methods:

Quantitative MR angiography (qMRA) was employed to measure flow rates in 15 major cerebral arteries of 83 healthy volunteers.
The cerebral arterial network was segmented into 12 regions, and regional flows were computed from measured arterial flows.

Main Results:

Mean total cranial flow was 949 ± 158 mL/min, and mean total cerebral blood flow was 695 ± 113 mL/min.
Mean regional flows for anterior and posterior circulation were 483 ± 87 mL/min and 212 ± 34 mL/min, respectively.
Flows were significantly lower in females compared to males for extracranial circulation, but not intracranial circulation.

Conclusions:

A partition tree of 12 cerebral circulation regions was successfully established using qMRA.
Mean regional flow values were determined for each identified region, providing a basis for clinical application.