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Published on: September 24, 2020
Sevoflurane for induction and intubation in children undergoing congenital cardiac surgery
1Department of Anaesthesiology, Cardiac Surgery, Escorts Heart Institute and Research Centre, Okhla Road, New Delhi, India. samirgirotra@hotmail.com.
Insights
Sevoflurane provides excellent conditions for nasal intubation in pediatric cardiac surgery patients. This anesthetic agent ensures hemodynamic stability and safety during induction and intubation procedures.
Area of Science:
- Anesthesiology
- Pediatric Cardiac Surgery
Background:
- Sevoflurane is an inhalational anesthetic agent commonly used in pediatric anesthesia.
- Assessing its efficacy and safety for endotracheal intubation in pediatric cardiac surgery is crucial.
Purpose of the Study:
- To prospectively evaluate the induction and intubation characteristics of sevoflurane in children undergoing congenital cardiac defect repair.
- To assess the safety and hemodynamic stability during sevoflurane-induced anesthesia and intubation.
Main Methods:
- Prospective study of 23 children (3 months to 6 years) undergoing cardiac surgery.
- Anesthesia induced with sevoflurane and nitrous oxide after chloral hydrate premedication.
- Nasal endotracheal intubation performed without neuromuscular blockers or opioids; induction/intubation times and conditions recorded.
Main Results:
- Excellent intubating conditions in 91.3% of patients, good in 8.7%.
- Mean induction time: 43.7 ± 4.57 seconds; mean intubation time: 149.1 ± 15.6 seconds.
- Hemodynamic parameters remained stable throughout, with no adverse airway events observed.
Conclusions:
- Sevoflurane facilitates rapid and effective induction and intubation in pediatric cardiac surgery.
- It provides excellent intubating conditions with preserved hemodynamic stability and a favorable safety profile.
Abstract:
The induction and intubation characteristics of sevoflurane were studied prospectively in 23 children, aged 3 months to 6 years (mean 24 +/- 20.25), undergoing repair of congenital cardiac defects. After premedication with syrup chloral hydrate (75mg/kg orally), anaesthesia was induced with 8% sevoflurane and 50% nitrous oxide in oxygen. Nasal endotracheal intubation was performed once the pupils were small and central, without the use of neuromuscular blocking agents or opioids. Characteristics of induction and intubating conditions were recorded. Induction time (from application of face mask to loss of eyelash reflex) was 43.7 +/- 4.57 secs (mean +/- SD). Mean intubation time was 149.1 +/- 15.6 secs. Intubating conditions were excellent in 21 patients (91.3%) and good in 2 patients (80.7%). Haemodynamic parameters (heart rate, rhythm, and systolic blood pressure) were recorded at loss of eyelash reflex, immediately before intubation and at 1, 3 and 5 min after intubation. All children remained haemodynamically stable throughout induction and there were no adverse airway events.
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