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Updated: Jul 11, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Sickness absence due to depressive symptoms.

P C Koopmans¹, C A M Roelen, J W Groothoff

¹Department of Occupational Health Services, ArboNed Noord-Oost Nederland, PO Box 141, 9700 AC Groningen, The Netherlands. petra.koopmans@arboned.nl

International Archives of Occupational and Environmental Health

|September 13, 2007

Summary

Depressive symptoms cause long sickness absences, averaging 200-213 days for Dutch workers. A 24% chronicity rate highlights the need for early intervention tools to manage prolonged work disability.

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Published on: April 26, 2024

Area of Science:

Occupational health
Psychiatry
Epidemiology

Background:

Limited data exists on the duration of sickness absence due to depression in the Dutch working population.
Understanding absence duration is crucial for effective workplace interventions and economic impact assessment.

Purpose of the Study:

To determine the duration of sickness absence episodes diagnosed as depression in the Dutch working population.
To identify factors influencing the length of absence due to depressive symptoms.

Main Methods:

Observational study analyzing 9,910 absence episodes diagnosed as depression.
Kaplan-Meier survival analysis was used to compute absence durations.
Data was collected from 15% of the Dutch working population between April 2002 and November 2005.

Main Results:

The mean sickness absence duration for depressive symptoms was 200 days for men and 213 days for women.
An estimated 24% of cases showed chronicity (absence exceeding 1 year).
Longer durations were observed in older employees, public/educational/health services, and smaller companies.

Conclusions:

Workers experiencing depressive symptoms face prolonged sickness absence, with a significant risk of chronic conditions.
Interventions aimed at early recognition and management of employees at risk for chronic depression are recommended.
The findings underscore the substantial impact of depression on work disability and the need for targeted workplace strategies.