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Eosinophilic colitis.

V R Velchuru1, M A B Khan, H B Hellquist

  • 1Department of Surgery, James Paget Hospital NHS Trust, Lowestoft Road, Gorleston, Great Yarmouth, NR31 6LA, UK. velchuru@hotmail.com

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
|September 13, 2007
PubMed
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Eosinophilic colitis, a rare inflammatory bowel disease, can lead to cecal volvulus obstruction. This case highlights a unique association requiring surgical intervention for this rare gastrointestinal condition.

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pathology

Background:

  • Eosinophilic colitis is a rare chronic inflammatory bowel condition with an unknown cause.
  • It is characterized by eosinophil infiltration into the colon wall.

Observation:

  • A 48-year-old female presented with symptoms of abdominal pain, constipation, and distension.
  • Clinical and radiological findings indicated a diagnosis of cecal volvulus.
  • Preoperative colonoscopic reduction of the volvulus was unsuccessful.

Findings:

  • Surgical exploration via laparotomy revealed the need for a right hemicolectomy with primary anastomosis.
  • Histological examination of the resected specimen confirmed diffuse eosinophilic infiltration, consistent with eosinophilic colitis.

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  • This represents the first reported case associating cecal volvulus with eosinophilic colitis.
  • Implications:

    • This case suggests a potential, previously unreported link between eosinophilic colitis and cecal volvulus.
    • It underscores the importance of considering rare gastrointestinal emergencies in patients with chronic inflammatory conditions.
    • Further research may elucidate the underlying mechanisms connecting these two conditions.