Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SADI-S Versus Distal OATB (SASI): Does the Duodenal Pathway Matter in Ileal-Level Single-Anastomosis Surgery?

Journal of laparoendoscopic & advanced surgical techniques. Part A·2026
Same author

Gastroesophageal Reflux Disease Outcomes after Sleeve Gastrectomy with One Anastomosis Transit Bipartition: A Systematic Review and Meta-analysis.

Obesity surgery·2026
Same author

Combined tenofovir, lamivudine, and dolutegravir treatment increases leptin and FABP4 expression in human subcutaneous adipose tissue.

Einstein (Sao Paulo, Brazil)·2026
Same author

Modified Polycaprolactone Films for Temporary Protection in Saline Conditions: A Preliminary Assessment.

Polymers·2026
Same author

12-month outcomes of GLP - 1 in severe pediatric obesity: real-world data.

Frontiers in endocrinology·2025
Same author

Endoscopic treatment of permanent end-jejunostomy stenosis with magnets.

Gastrointestinal endoscopy·2025

Related Experiment Video

Updated: Jul 11, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Bariatric surgery in pediatrics--is it time?

Manoel Carlos Prieto Velhote1, Durval Damiani, Sergio Santoro

  • 1Pediatric Surgery, Instituto da Criança, Hospital das Clinicas, São Paulo University Medical School, Brazil. mvelhote@uol.com.br

Journal of Pediatric Endocrinology & Metabolism : JPEM
|September 14, 2007
PubMed
Summary

Morbid obesity is increasing globally, especially in adolescents. While lifestyle changes are primary, bariatric surgery offers significant weight loss and metabolic improvement for severe cases, despite potential complications.

More Related Videos

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
10:05

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice

Published on: March 20, 2017

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

Related Experiment Videos

Last Updated: Jul 11, 2026

Sleeve Gastrectomy in Mice using Surgical Clips
05:16

Sleeve Gastrectomy in Mice using Surgical Clips

Published on: November 14, 2020

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
10:05

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice

Published on: March 20, 2017

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
08:50

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice

Published on: October 18, 2024

Area of Science:

  • Endocrinology
  • Surgical Gastroenterology
  • Public Health

Background:

  • Rising global obesity rates necessitate advanced interventions.
  • Morbid obesity is increasingly prevalent in adolescents.
  • Conservative treatments show limitations in managing severe obesity.

Purpose of the Study:

  • To review and discuss various bariatric surgical approaches for morbid obesity.
  • To analyze the advantages and disadvantages of different surgical techniques.
  • To highlight the role of bariatric surgery in managing severe obesity cases.

Main Methods:

  • Review of current bariatric surgical procedures.
  • Analysis of short- and long-term complication rates.
  • Evaluation of efficacy in achieving significant weight loss and metabolic improvement.

Main Results:

  • Bariatric surgery can lead to substantial weight loss and improved metabolic status.
  • Various surgical techniques exist, each with unique risk profiles.
  • Complications, though potentially severe, are a consideration in surgical decision-making.

Conclusions:

  • Bariatric surgery is a viable option for select morbidly obese patients, particularly adolescents.
  • Careful consideration of surgical risks and benefits is crucial.
  • Further research into optimizing surgical outcomes is warranted.