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A dual near-infrared pH fluorescent probe and its application in imaging of HepG2 cells
1College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Shandong Normal University, Jinan 250014, P. R. China. tangb@sdnu.edu.cn
Chemical Communications (Cambridge, England)
|September 14, 2007
Abstract:
A dual near-infrared pH fluorescent probe has been designed, synthesized and applied to HepG2 cells, with a pK(a) value of 5.14 under acidic conditions and 11.31 under basic conditions, which is valuable for studying acidic organelles in living cells and pH changes in chemical systems.
