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Boron intake and prostate cancer risk
Alejandro Gonzalez1, Ulrike Peters, Johanna W Lampe
1Cancer Prevention Pragram, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.
Cancer Causes & Control : CCC
|September 14, 2007
Summary
This study found no evidence that boron intake prevents prostate cancer. Further research is needed to understand boron's potential role in prostate cancer prevention.
Area of Science:
- Oncology
- Nutritional Science
- Epidemiology
Background:
- Experimental studies suggest boron may have a role in preventing prostate cancer.
- A prior small study indicated lower prostate cancer risk with higher boron intake.
Purpose of the Study:
- To evaluate the association between boron intake and prostate cancer risk.
- To investigate if dietary boron or boron from supplements impacts prostate cancer incidence.
Main Methods:
- Utilized the VITamins And Lifestyle (VITAL) cohort study data.
- Assessed boron intake using food frequency questionnaires and a boron database.
- Followed 35,244 men for prostate cancer development over several years.
Main Results:
- No significant association was found between boron intake (dietary or total) and prostate cancer risk.
- The hazard ratio for prostate cancer in the highest versus lowest boron intake quartile was 1.17 (95% CI 0.85, 1.61).
- No specific boron-rich foods were linked to reduced prostate cancer risk.
Conclusions:
- This large cohort study does not support a preventive role for boron intake in prostate cancer.
- More research is necessary to clarify the relationship between boron and prostate cancer.
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