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Published on: February 2, 2024
Iridoids from Gardenia jasminoides
Consolacion Y Ragasa1, Leslie Elline N Pimenta, John A Rideout
1Chemistry Department, De La Salle University, Manila, Philippines. ragasac@dlslu.edu.ph
Abstract:
The dichloromethane extract of the air-dried flowers of Gardenia jasminoides Ellis. afforded a new iridoid natural product (1), and a diastereomeric mixture of two new iridoids (2a and 2b) in a 2 : 1 ratio. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests on 1 indicated that it was moderately active against Candida albicans; slightly active against E. coli, Pseudomonas aeruginosa, Staphylococcus. aureus, and Trichophyton mentagrophytes; and inactive against Bacillus subtilis and Aspergillus niger.
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