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Updated: Aug 22, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
[Evolution of the detection of interventricular septal defect]
F Sampayo1, J Quininha, M Teixeira
1Serviço de Cardiologia Pediátrica, Hospital de Santa Marta, Lisboa.
Insights
Early detection of ventricular septal defect in children significantly improved after 1972. This study observed 1274 pediatric cases, highlighting the importance of timely intervention to prevent pulmonary vascular disease.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Defects
- Public Health
Context:
- Observational study of 1274 infants and children with isolated ventricular septal defect (VSD) from 1969 to 1986 in Portugal.
- Patients ranged from 3 days to 12 years, excluding those with syndromes.
- Focus on the critical need for early detection to prevent fixed pulmonary arterial resistance.
Purpose:
- To analyze the annual variation in the age of referral for pediatric VSD cases.
- To assess the impact of early detection and referral strategies on patient outcomes.
- To identify trends in VSD management over a 17-year period.
Summary:
- The study observed a cohort of 1274 children with VSD over 17 years.
- Referral age analysis revealed significant improvements starting in 1972.
- A steady, faster improvement in referral age was noted in the last 7 years of the study.
Impact:
- Demonstrates the positive effect of improved early detection and referral practices for pediatric VSD.
- Provides evidence for the benefits of timely intervention in preventing severe complications like pulmonary vascular disease.
- Highlights the long-term trends and improvements in managing congenital heart defects in a specific population.
Abstract:
From 24.10.1969 to 31.12.1986, seventeen years, 1274 infants and children with proven isolated ventricular septal defect were observed and followed in Pediatric Cardiology of Santa Marta Hospital. There were 659 males and 615 females, ranging from 3 days to 12 years, born in portuguese territory and without syndromes. As early detection and referring is crucial to prevent pulmonary vascular disease with fixed pulmonary arterial resistance, the annual variation of the referring age was studied. The results improved since 1972 with a steady faster improvement during the last 7 years of the study.
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