Related Experiment Videos
Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19)
U R Kees1, M T Mulcahy, M L Willoughby
1Department of Haematology-Oncology, Western Australian Research Institute for Child Health, Princess Margaret Hospital, Perth.
The American Journal of Pediatric Hematology/Oncology
|January 1, 1991
Abstract:
We report here a rare case of intrathoracic undifferentiated carcinoma in an 11-year-old girl. The biopsy tissue stained with antibodies against cytokeratin and carcino-embryonic antigen. The same staining was obtained using a cell line, PER-403, which was derived from the tumor. DNA from PER-403 cells was tested for the presence of Epstein-Barr virus genes, yielding a negative result. The cytogenetic analysis found a translocation t(15;19) (p12;q13), which has not previously been described in a carcinoma.