Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Spermatids are regulators of Sertoli cell function.

B Jégou1

  • 1Groupe d'Etude de la Reproduction chez le Mâle, INSERM/CJF 91-04, Université de Rennes I, France.

Annals of the New York Academy of Sciences
|January 1, 1991
PubMed
Summary

Spermatids regulate Sertoli cell function through anatomical structures and secreted factors. This interaction is vital for gene expression and secretory function throughout male reproductive development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Receptivity of the human male and female fetal caudal genital ligament to gonadal hormones.

Reproduction (Cambridge, England)·2026
Same author

High lead level in the Alps in XIXth century, learning from the analysis of 138 historical hair stands.

Chemosphere·2021
Same author

Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis.

Human reproduction (Oxford, England)·2020
Same author

Myelinosome-like vesicles in human seminal plasma: A cryo-electron microscopy study.

Cryobiology·2019
Same author

A case of bacteriemic mediastinitis due to Prevotella buccae after cardiac surgery.

Anaerobe·2019
Same author

RNA profiling of human testicular cells identifies syntenic lncRNAs associated with spermatogenesis.

Human reproduction (Oxford, England)·2019

Area of Science:

  • Reproductive Biology
  • Cell Biology
  • Developmental Biology

Background:

  • Spermatids are crucial for regulating Sertoli cell function.
  • Specific anatomical structures mediate the interaction between spermatids and Sertoli cells.
  • These structures and interactions evolve during spermiogenesis.

Purpose of the Study:

  • To elucidate the role of spermatids in regulating Sertoli cell gene expression and secretory function.
  • To understand the mechanisms underlying spermatid-Sertoli cell communication.
  • To investigate the age-dependent and evolutionarily conserved aspects of this interaction.

Main Methods:

  • The study likely involved histological and ultrastructural analyses of the spermatid-Sertoli cell interface.
  • Investigated the secretion of soluble factors by early spermatids.
  • Examined the role of late spermatids in Sertoli cell conformational changes and phagocytosis of residual bodies.

Main Results:

  • Spermatids significantly influence Sertoli cell gene expression and secretory function.
  • Early spermatid effects are partly mediated by secreted factors.
  • Late spermatids impact adult Sertoli cell secretion through conformational changes and residual body phagocytosis, a conserved mechanism.

Conclusions:

  • Spermatids are essential regulators of Sertoli cell function across different life stages.
  • The interaction between spermatids and Sertoli cells is mediated by dynamic anatomical structures and cellular processes.
  • Understanding these interactions provides insights into male reproductive health and spermiogenesis.

Related Experiment Videos