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Updated: Jul 11, 2026
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A Silicon-tipped Fiber-optic Sensing Platform with High Resolution and Fast Response
Published on: January 7, 2019
High-resolution photonic bandgap fiber-based biochemical sensor
Jian Sun1, Chi-Chiu Chan, Xin-Yong Dong
1Nanyang Technological University, School of Chemical and Biomedical Engineering, Division of Bioengineering, Singapore 637457. sunjian@pmail.ntu.edu.sg
Journal of Biomedical Optics
|September 18, 2007
Summary
Photonic bandgap fibers (PBGF) show promise for label-free biosensing. These fibers exhibit significant wavelength shifts in response to refractive index changes, enabling highly sensitive detection with minimal sample volume.
Area of Science:
- Optics and Photonics
- Biomedical Engineering
- Materials Science
Background:
- Photonic bandgap fibers (PBGF) offer unique light manipulation properties.
- Biomedical sensing requires sensitive and label-free detection methods.
Purpose of the Study:
- To demonstrate the potential of PBGF for biomedical sensing applications.
- To investigate the performance of PBGF in detecting changes in ambient refractive index.
Main Methods:
- Fabrication and characterization of PBGF.
- Measurement of wavelength shift in the photonic bandgap edge (PBE) with varying refractive indices.
- Analytical modeling of PBGF optical response.
Main Results:
- A significant blue wavelength shift of 280 nm was observed in the PBE for a refractive index change from 1.333 to 1.39.
- Experimental results closely matched analytical predictions.
- Potential for high sensitivity (0.1 nmol/L) with low sample consumption (< 1 microL).
Conclusions:
- PBGF are suitable for label-free biomedical sensing.
- Combining PBGF with immobilization techniques and biorecognition elements can create novel biosensors.
- The demonstrated PBGF technology offers a promising platform for sensitive and efficient biosensing.
