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Updated: Jul 11, 2026

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Published on: June 2, 2014
Associations between migraine and cardiovascular disease
1Division of Aging, Brigham & Women's Hospital, 1620 Tremont Street, 3rd floor, Boston, MA 02120-1613, USA. tkurth@rics.bwh.harvard.edu
Migraine with aura, a neurological condition, is linked to a higher risk of ischemic stroke and other vascular events. Research is exploring the complex biological mechanisms behind this association.
Area of Science:
- Neurology
- Cardiology
- Epidemiology
Background:
- Migraine is a common neurological disorder.
- Migraine with aura involves neurological symptoms, especially visual disturbances.
- Existing studies suggest a link between migraine with aura and increased ischemic stroke risk.
Purpose of the Study:
- To review the epidemiological evidence connecting migraine with ischemic vascular events.
- To discuss potential biological mechanisms underlying this association.
- To outline the potential consequences of migraine with aura on vascular health.
Main Methods:
- Literature review of population-based and prospective studies.
- Analysis of epidemiological data on migraine and vascular events.
- Exploration of proposed biological and genetic mechanisms.
Main Results:
- Consistent association found between migraine with aura and increased risk of ischemic stroke.
- Emerging evidence links migraine with aura to other ischemic vascular events, including coronary heart disease.
- The precise biological mechanisms remain unclear but likely involve shared risk factors and complex interactions.
Conclusions:
- Migraine with aura is associated with an elevated risk of ischemic vascular events.
- Further research is needed to elucidate the complex mechanisms and guide preventative strategies.
- Understanding this link is crucial for managing patients with migraine and assessing their cardiovascular risk.
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