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Identification of a novel allele HLA-DQB1*0622
1Department of Pathology and Laboratory Medicine, All Children's Hospital, St. Petersburg, FL 33701, USA. changy@allkids.org
Tissue Antigens
|September 18, 2007
Abstract:
A novel human leukocyte antigen-DQ allele, DQB1*0622, was identified in a bone marrow transplantation candidate. DQB1*0622 differs from DQB1*0609 by two nucleotide differences in exon 2, position 122 (A-->T) and 177 (A-->G). The difference at position 122 resulted in an amino acid change (Tyrosine to Phenylalanine). However, the difference at position 177 did not cause any amino acid change.
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