Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Spectroscopic imaging from spatially-encoded single-scan multidimensional MRI data.

Assaf Tal1, Lucio Frydman

  • 1Department of Chemical Physics, Weizmann Institute of Science, 76100 Rehovot, Israel.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|September 18, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultra-Wideline 2D Correlations Among Low-γ Species in Solid-State NMR via the Progressive Saturation of a Common Proton Reservoir.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

On the effects of hyperpolarized water-based dissolution on the solute and solvent <sup>1</sup>H NMR spectra of small molecules.

Physical chemistry chemical physics : PCCP·2026
Same author

Do Symptom Domains Have Similar Cellular Underpinnings Across Psychiatric Diagnoses: Evidence from 3D Hippocampal MR Spectroscopy.

bioRxiv : the preprint server for biology·2026
Same author

14.1 T Liquid-State <sup>19</sup>F Overhauser Dynamic Nuclear Polarization in an Analytical Organic Setting.

Journal of the American Chemical Society·2026
Same author

Assessing the treatment of pancreatic ductal adenocarcinoma by deuterium metabolic imaging: a preclinical study.

Magma (New York, N.Y.)·2026
Same author

Enhanced Sensitivity and Resolution in Biomolecular CEST NMR Experiments Using the Extended Hadamard Encoding Scheme.

Analytical chemistry·2025
Same journal

Localization-driven exchange contrast in diffusion exchange spectroscopy.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

4.5 Tesla superconducting miniature magnet in liquid nitrogen.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Folding and unfolding dynamics of a DNA aptamer studied by heteronuclear <sup>1</sup>H-<sup>13</sup>C correlation zz-exchange spectroscopy.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Multi-spin control from one-spin pulses.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Altering MRI rotating frame relaxations by changing the truncation level of Hyperbolic Secant pulse.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Effects of proton exchange on the lifetimes of long-lived states in aliphatic chains.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
See all related articles

A new magnetic resonance imaging (MRI) method uses signal phase to simultaneously capture spectroscopic and spatial information in a single scan. This advanced technique provides high-resolution data without increasing scan time or complexity.

Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Spectroscopic Imaging
  • Medical Physics

Background:

  • Traditional MRI protocols often require separate scans for spatial and spectroscopic information.
  • Acquiring multidimensional data typically increases scan time and complexity.
  • Existing single-scan methods may struggle with magnetic field inhomogeneities.

Purpose of the Study:

  • To introduce a novel single-scan protocol for retrieving multidimensional magnetic resonance images.
  • To demonstrate that signal phase modulation encodes chemical shift information, enabling spectroscopic resolution.
  • To show this method enhances data quality even with magnetic field variations.

Main Methods:

  • Utilizing spatial encoding of spin interactions via progressive dephasing and refocusing gradients.

Related Experiment Videos

  • Analyzing both the magnitude (spatial distribution) and phase (chemical shift) of the time-domain signal.
  • Incorporating "RF shimming" for magnetic field inhomogeneity compensation.

    • Main Results:

    • The absolute signal magnitude provides spatial imaging information.
    • The signal phase modulation reveals chemical shift information, enabling spectroscopic resolution.
    • High-resolution spectral and imaging data were achieved in phantoms without added scan time or complexity.

    Conclusions:

    • A single-scan protocol can acquire both spatial and spectroscopic MRI data simultaneously.
    • Phase modulation analysis offers a cost-free method for enhanced spectroscopic imaging.
    • The technique shows promise for high-quality imaging in challenging magnetic field conditions.