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Updated: Jul 11, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Indications for surgery in degenerative mitral valve disease
Hartzell V Schaff1, Rakesh M Suri, Maurice Enriquez-Sarano
1Divisions of Cardiovascular Surgery and Cardiovascular Diseases, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA. schaff@mayo.edu
Early surgical correction of severe mitral regurgitation improves patient outcomes. Mitral valve repair offers superior benefits over replacement, enhancing cardiac function and survival.
Area of Science:
- Cardiology
- Cardiac Surgery
- Diagnostic Imaging
Background:
- Significant advancements in managing mitral regurgitation (MR) have occurred.
- Doppler echocardiography is crucial for assessing MR severity and its impact on cardiac health.
- Natural history studies reveal severe MR increases risks of cardiac death, heart failure, and atrial fibrillation.
Purpose of the Study:
- To review the progress in mitral regurgitation management over the past decade.
- To emphasize the benefits of early surgical intervention for severe MR.
- To compare outcomes of mitral valve repair versus replacement.
Main Methods:
- Review of natural history studies on mitral regurgitation.
- Analysis of outcomes data for patients undergoing surgical correction.
- Utilizing Doppler echocardiography for MR quantification and cardiac assessment.
Main Results:
- Early surgical correction of severe mitral regurgitation is associated with improved short-term and long-term patient outcomes.
- Mitral valve repair demonstrates clear advantages over valve replacement.
- Repair leads to better regression of left heart dimensions and improved left ventricular function.
Conclusions:
- Early surgical intervention is recommended for severe mitral regurgitation.
- Mitral valve repair is the preferred surgical option, offering superior functional and survival benefits.
- Continued progress in diagnostic tools and surgical techniques enhances MR patient management.
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