Related Experiment Video
Updated: Jul 11, 2026
17:13
Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain
Published on: October 22, 2017
In praise of tedious anatomy
Joseph T Devlin1, Russell A Poldrack
1Centre for Functional Magnetic Resonance of the Brain, University of Oxford, UK. devlin@fmrib.ox.ac.uk
Neuroimage
|September 18, 2007
Summary
Accurate functional neuroimaging requires precise localization to individual brain anatomy. Standardized methods and atlases are crucial for reliable mapping of brain function to structure, overcoming individual variability.
Area of Science:
- Neuroimaging
- Neuroanatomy
- Brain Mapping
Background:
- Functional neuroimaging aims to map brain activity to anatomical structures.
- Accurate localization is essential for the validity of functional neuroimaging findings.
- Individual anatomical variability poses a challenge to precise functional localization.
Purpose of the Study:
- To review methods for localizing functional activation to neuroanatomy.
- To propose a gold standard for functional localization.
- To suggest improvements for reporting functional localization in neuroimaging research.
Main Methods:
- Review of existing functional neuroimaging localization techniques.
- Analysis of the impact of individual anatomical variability.
- Discussion of neuroanatomical knowledge and atlases for localization.
Main Results:
- Localization to an individual's or group's own anatomy is proposed as the gold standard.
- Automated localization methods may lack the necessary accuracy due to inter-individual differences.
- A need for standardized reporting methods, including a common standard space, is identified.
Conclusions:
- Precise neuroanatomical localization is fundamental for functional neuroimaging.
- Utilizing individual anatomy and established atlases ensures greater accuracy.
- Convergence on common reporting standards is necessary for advancing the field.
Related Concept Videos
01:24Overview of Anatomy and Physiology
Human anatomy is the scientific study of the body's structures. Some of these structures are very small and can only be observed and analyzed with the assistance of a microscope. Other larger structures can readily be seen, manipulated, measured, and weighed. The word "anatomy" comes from a Greek root that means "to cut apart." Human anatomy was first studied by observing the body's exterior and the wounds of soldiers and other injuries. Later, physicians were allowed to dissect the bodies of...
01:17Gross Anatomy of Bone
The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in adults, it...
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in adults, it...
02:03Anatomy of the Circulatory System
The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.
01:12Gross Anatomy of Skeletal Muscles
The connective tissues play a significant role in arranging the muscle fibers into a hierarchical structure that forms a complete muscle. Consider a muscle like the bicep brachii, commonly called the bicep. This muscle comprises thousands of muscle fibers enclosed by a protective layer of connective tissue called the endomysium. The endomysium is primarily composed of reticular fibers, a type of thin collagen fiber. It allows the exchange of nutrients and waste products at the fiber level,...
01:20Anatomy of Blood Vessels
The vascular system, an integral part of the circulatory system, comprises various blood vessels that play crucial roles in maintaining the body's homeostasis. These blood vessels form a complex and efficient circulatory network. The three primary categories of blood vessels are the arteries, veins, and capillaries.
Arteries
Arteries circulate oxygenated blood from the heart, except the pulmonary artery, which transports deoxygenated blood to the lungs. Large arteries, such as the aorta, have...
Arteries
Arteries circulate oxygenated blood from the heart, except the pulmonary artery, which transports deoxygenated blood to the lungs. Large arteries, such as the aorta, have...
00:55Skeletal Muscle Anatomy
Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.