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Updated: Jul 11, 2026
05:53
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
[Dementia complex due to HIV disease and aging]
1Service de Neurologie, Fondation Adolphe de Rothschild, Paris, France. amoulignier@fo-rothschild.fr
Psychologie & Neuropsychiatrie Du Vieillissement
|September 18, 2007
Summary
The epidemiology of human immunodeficiency virus (HIV) is shifting, with more older adults getting infected and aging with the virus. HIV-associated dementia is evolving due to advanced treatments.
Area of Science:
- Neurology
- Infectious Diseases
- Geriatrics
Context:
- Epidemiology of human immunodeficiency virus (HIV) infection is changing.
- Increasing incidence of new HIV infections in individuals over 50.
- Aging population of individuals living with HIV due to effective antiretroviral therapies.
Purpose:
- To review the epidemiology, pathogenesis, clinical features, diagnosis, and management of HIV-associated dementia.
- To explore the impact of highly active antiretroviral therapies (HAART) and immune reconstitution on HIV dementia.
- To examine the relationship between HIV dementia, cognitive disorders, and aging.
Summary:
- Recent shifts in HIV epidemiology include increased infections in older adults and an aging cohort on HAART.
- HIV-associated dementia, though modified by HAART, remains a significant neurological complication.
- This review details the multifaceted aspects of HIV dementia, from its origins to its management in aging populations.
Impact:
- Provides a comprehensive overview of HIV dementia in the context of an aging HIV population.
- Highlights the evolving clinical landscape of neurological complications in HIV.
- Informs clinical practice regarding the diagnosis and management of cognitive disorders in older adults with HIV.
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