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Effects of fasting on saliva composition.
1Dental Faculty, University of Malaya, Kuala Lumpur.
The Journal of Nihon University School of Dentistry
|December 1, 1991
Summary
Fasting significantly reduces salivary flow rate and increases nitrite concentration. However, calcium, phosphate, and protein levels in saliva remain largely unchanged, regardless of sex.
Area of Science:
- Oral biology
- Human physiology
Background:
- Saliva plays a crucial role in maintaining oral health.
- Understanding salivary composition under different physiological conditions is important.
Purpose of the Study:
- To compare salivary flow rate and concentrations of calcium, phosphate, protein, and nitrite in fasting versus non-fasting states.
- To investigate potential sex-based differences in salivary parameters.
Main Methods:
- Whole unstimulated saliva was collected from participants under two conditions: fasting (≥6 hours without food/water) and control (within 1 hour after food intake).
- Salivary flow rate, calcium, phosphate, protein, and nitrite concentrations were measured and compared between conditions and sexes.
Main Results:
- Fasting saliva flow rate was significantly lower (0.098 ml/min) compared to control (0.208 ml/min), with no sex differences.
- Nitrite concentration was 50% higher in fasting saliva (p<0.05).
- Protein concentration showed a non-significant decrease during fasting. Calcium and phosphate concentrations were comparable between fasting and control saliva, with no significant sex variations.
Conclusions:
- Fasting alters salivary flow rate and nitrite levels, but not significantly calcium, phosphate, or protein concentrations.
- These findings contribute to understanding salivary physiology and its response to nutritional status.