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Updated: Jul 11, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

[Standard electrocardiography and Holter monitoring changes in acromegalic patients]

Romuald Twardowski1, Józefa Dabek, Daniel Jakubowski

  • 1Slska Akademia Medyczna w Katowicach, Katedra i Klinika Kardiologii.

Polski Merkuriusz Lekarski : Organ Polskiego Towarzystwa Lekarskiego
|September 19, 2007
PubMed

Insights

Patients with acromegaly experience significant electrical heart disturbances, including prolonged QT intervals and arrhythmias. Early cardiac monitoring by a cardiologist is recommended for these patients.

Area of Science:

  • Cardiology
  • Endocrinology

Background:

  • Hormonal imbalances, particularly in the thyroid, parathyroid, adrenal, and gonadal glands, are well-researched regarding circulatory effects.
  • The relationship between growth hormone and the cardiovascular system requires further investigation.

Purpose of the Study:

  • To describe cardiovascular complications in acromegaly detectable by standard electrocardiogram (ECG) and 24-hour Holter monitoring.

Main Methods:

  • Compared 28 acromegaly patients (15 with hypertension) with 20 hypertensive patients and 20 healthy controls.
  • All subjects underwent physical examination, resting ECG, and 24-hour Holter monitoring.
  • Evaluated heart rate, arrhythmias, QRS, QT, QTc intervals, and atrial/ventricular hypertrophy.

Main Results:

  • Acromegaly patients exhibited significant electrical cardiac disturbances.
  • Substantial QT and QTc interval prolongation and QRS complex prolongation were observed.
  • Supraventricular and ventricular arrhythmias were more frequent in acromegaly patients.

Conclusions:

  • Acromegaly is associated with significant, potentially life-threatening electrical heart function disturbances.
  • Acromegaly patients warrant early and regular cardiological monitoring.
Abstract

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